Showing posts with label British Journal of Psychiatry. Show all posts
Showing posts with label British Journal of Psychiatry. Show all posts

Sunday, 29 January 2012

British Journal of Psychiatry: ^NOT 'Prestigious'

While writing yesterday's blogpost on Vellacott's references section, I found that the current issue of the British Journal of Psychiatry revisits the Coleman (with four citations from Vellacott) controversy with letters to the editor, the editors' response, and author's reply.

They are not yet available online, but available to subscription holders and to a grand friend of DJ! with access to a university sub -- thanks again, godammitkitty.

Here's the abstract of her paper with previous critical letters to the editor.

The criticism focuses on three major shortcomings in her work which found (astoundingly):
Results: Women who had undergone an abortion experienced an 81% increased risk of mental health problems, and nearly 10% of the incidence of mental health problems was shown to be attributable to abortion.


Methodology

Logic

Bias

I won't address methodology, not being a statistician, but I'll quote one para in which I count 10 negatives:
This quantitative synthesis and meta-analysis did not follow the robust methodologies now generally accepted for systematic reviews.2 There is no detail of the search strategy including search terms; the strategy is not comprehensive (only two databases included); other strategies to search the literature, including citation tracking, hand searching and contacting authors and experts in the field to try to minimise publication bias, were not carried out; and there was no assessment or rating of the quality of included studies, so that only those of at least reasonable quality are included in the meta-analysis. This is particularly important here as many of the primary studies included in this review have significant methodological limitations, including non-prospective design, non-standardised measures of mental disorders, lack of adjustment for pre-existing mental illness, lack of adjustment for other key confounders (e.g. social deprivation), non-comparability of exposed and non-exposed groups, and selection bias. This is especially concerning, given that previous reviews raised serious methodological concerns about some of the included studies, and came to different conclusions when these were excluded from analyses.3–5 Furthermore, results from several of the included studies linking abortion to mental health problems have since been re-analysed by other researchers. These studies, using the same data, have less biased sample selection techniques and control for pre-pregnancy factors known to influence poor mental health outcomes (i.e. rape history) and have found no significant links between abortion and subsequent poor mental health.6,7

-- Louise M. Howard, Kylee Trevillion, and Trine Munk-Olsen

Kathryn M. Abel and Peter Brocklehurst single out her use of something called population atributable risk (PAR).
In Coleman’s synthesis, the PAR measure has been applied inappropriately and, we believe, reported misleadingly.

There is much much more of this sort of criticism, featuring the words 'not', 'failed', and so on. It's pretty apparent she fucked up majorly in the methodology.

Now, on logic, I'm on stronger ground. As I argued at the time, correlation does NOT equal causation. Something, Abel and Brocklehurst also note:
Second, in the first paragraph of the Discussion (p.183), Coleman states with apparent certainty that ‘. . . nearly 10% of the incidence of mental health problems was shown to be directly attributable to abortion.’ This is about as unambiguous a statement of causality as could possibly be made, in the face of clear guidance on the potential pitfalls of drawing such conclusions when applying the PAR.

Well, duh. The correlation/causality fallacy is dealt with early in basic logic, classic example being: 'If the streets are wet, it's raining'.

I'm ready to sit corrected, but it seems to me that her flouting this basic basic basic law of logic is what got up most scientists' (and non-scientists') noses.

Next, her declaration of 'conflict of interest' was, incredibly: 'None.'

Julia H. Littell and James C. Coyne say:
An article in the British Journal of Psychiatry6 calls attention to the importance of non-financial conflicts of interest in the psychiatric literature. Coleman has at least two types of conflict of interest here. Among the most important of such conflicts is an agenda-driven bias, by which authors seek to influence legislation and social policy. David Reardon is a co-author with Coleman on seven articles included in the review and an author on an additional study in the review that does not involve Coleman as a co-author. Reardon is quite explicit about his agenda to instil fear of abortion as a way of facilitating passage of anti-abortion legislation.7

Coleman is the first author on 6 studies and co-author on 5 additional studies in her review; thus, she authored or co-authored fully half of the 22 studies included. According to the Cochrane Handbook,8 this is another potential conflict of interest, since it may ‘unduly influence judgements made in a review (concerning, for example, the inclusion or exclusion of studies, assessments of the risk of bias in included studies or the interpretation of results) . . . This should be disclosed in the review and, where possible, there should be an independent assessment of eligibility and risk of bias by a second author with no conflict of interest.’ Coleman did not obtain an independent assessment of the studies she authored or co-authored, nor did she acknowledge these conflicts in the review.

That's enough for now, except to note that David Reardon and Fergusson et al., (the latter also among the references provided by Vellacott) both defend her. And they are the only ones to do so. Surprise.

Here are Littel and Coyne again:
It is unclear how this paper got through peer review at the Journal. It appears that peer reviewers and the Editor ignored published standards for systematic reviews and meta-analyses. Given the serious methodological flaws contained in Coleman’s review and the author’s failure to report obvious conflicts of interest, we believe the article should be retracted.

Let's hear from the editor of the 'prestigious journal' itself, shall we (emphasis and parenthetical comments mine)?
The article by Coleman1 was submitted in October 2010 and accepted for publication in March 2011, so predated the Munk-Olsen paper [yet another paper finding NO causality] paper ,2 as Coleman has indicated in her reply below. The handling editor was W.W. [Waquas Waheed] and the paper was accepted after revision with two reviewers supporting publication and one recommending rejection. It was recognised that the paper was likely to attract attention and P.T. [Peter Tyrer] suggested that a commentary should be published alongside the article. Unfortunately the major concurrent work [guess what it concluded] on this subject (commissioned by the Department of Health) had not then been completed and it was felt unfair to delay publication, so the article appeared without comment. Dr Coleman stated that she had no conflicts of interest to declare and when invited to revise this view subsequently when reminded of our guidance again reiterated this. She has again defended this in her letter; readers are free in the light of these full statements to come to their own conclusions. The failure to declare an interest is not a reason for retracting a systematic review even if failure was unequivocally demonstrated, and this situation is very different from other ones in which the publication of a paper has been retracted.3 [This footnote goes to the infamous Lancet retraction of the autism/vaccine fraud] We have nevertheless decided to give new guidance for the preparation of reviews in our authors’ instructions so there is greater clarity for both authors and reviewers. The correspondence and commentary in this issue indicates the importance of the subject and the value of an active correspondence column in a journal; it is not a reason to avoid the publication of a controversial subject.

Shorter: We didn't want to wait; it was going to generate (fun!) controversy; so what she lied; but we're changing the rules anyway.

Weasels.

But the real fun comes in Priscilla's defense of herself. She's NOT biased. Everyone else is.
By raising concerns of publication bias and attempting to undermine the credibility of an individual researcher who managed to publish in a high-profile journal, several people have sought to shift attention from the truly shameful and systemic bias that permeates the psychology of abortion. Professional organisations in the USA and elsewhere have arrogantly sought to distort the scientific literature and paternalistically deny women the information they deserve to make fully informed healthcare choices and receive necessary mental health counselling when and if an abortion decision proves detrimental.


To recap: bad science, conflict of interest, sloppy review, poor editorial oversight, only defenders also fetus fetishists = ALL GOOD.

I can't wait to hear what James Coyne and PZ Myers will have to say.

For my part, the word 'prestigious' will never appear in front of the words 'British Journal of Psychiatry' again. I'm thinking maybe 'shitty' or 'sensation-seeking' or 'weaselly'.

Aside: Priscilla Coleman is something of a hobby here at DJ! That link demonstrates the strength of our interest.

Saturday, 28 January 2012

Anti-Choice: Suckers for Scientists for Hire

(Whoa. This got long. Sorry.)

As promised, we take up the matter of the 'ignored' information in the CTV investigation into a fake clinic, as alleged in the eight-page press release issued by Maurice Vellacott.

By the way, Kady O'Malley had this to say about it.
I believe Maurice Vellacott may have just sent out the longest press release in the history of Canadian parliamentary democracy.

Among many, here's the complaint about bias. (I don't like Scribd. One can't copy and paste. Grrr.)
'The report ignored the scientific literature referenced in the centres' brochures which substantiates the centres' claims that abortion is associated with increased physical and psychological health risks.'

So, one of the eight pages is devoted to providing that missing information. There are eleven references. I looked them all up. Three seem legit, if not quite saying what Vellacott implies.

For example, the one by Ostbye. T., et al. is a simple comparison on abortion outcomes by location, i.e. looking into whether women have fewer complications from abortions performed in hospitals as opposed to clinics. It has nothing to do with abortion risks as such*.

Two, Moreau, C., et al. and Shah and Zao, focus on the relationship between previous abortion and risks of subsequent pre-term or low-weight delivery.

Again, both seem legit and do find a correlation. However, the first is based on French data from 1997, specifically because French women have a higher rate of abortion than many. The second is based on only 37 cases. Both caution that more study is necessary on the topic especially into what manner of abortion and what sorts of complications are also associated with low-weight or pre-term delivery. Not terribly damning, in other words, but at least legit.

Which is way more than can be said for the other eight.

Joel Brind is 'a leading advocate of the abortion-breast cancer hypothesis', which has been debunked countless times. 'Nuff said. Moving on. . .

A PDF of the Fergusson, D.M., et al. paper is available at the Toronto-based de Veber Institute. 'What's that? you ask?
The deVeber Institute for Bioethics and Social Research conducts and disseminates research on topics connected to human life in its biological, social and ethical dimensions. These topics are selected for study depending on emerging medical, technological and social developments. In undertaking this work the Institute believes that a sense of the inherent value and dignity of human life and of the human person as an end and not a means is a foundational perspective to bring to bear on its work.

A glance at its current projects (abortion and breast cancer, abortion and mental health, abortion and infertility) confirms: yes, another bogus anti-choice science for hire gang.

(BTW, like other such echo-chambers for lies, the site also cites the Ostbye study, but lies about its purpose and conclusions: 'A study conducted by the College of Physicians and Surgeons of Ontario shows that after induced abortion there is a 4 times increase in medical admissions and a 5 times increase in surgical admissions to the hospital.')

The Ring-Cassidy and Gentles paper is also associated with the de Veber Institute, its authors being principals there. Ring-Cassidy is a psychologist with a 'continued interest in Catholic Psychology and has taken American Psychological Association Continuing Credits in this area', while 'Ian Gentles is a Professor of History at York University's Glendon College and at Tyndale University College, and is a Fellow of the Royal Historical Society.' Yup, fully qualified to research 'women's health after abortion'.

Now we come to Angela Lanfranchi whose abortion=breast cancer paper was published in The Linacre Quarterly. Never heard of this prestigious medical journal? Me neither.
Linacre Quarterly, established in 1932, is a peer-reviewed academic journal published by the Catholic Medical Association. The journal primarily focuses on the relationship between medicine and spirituality and in particular on medical ethics.

An example of how the journal approaches both religious and medical issues is provided by an article in the August 2006 issue that discusses the medical aspects of crucifixion, given that the Crucifixion of Jesus is a central element of the Roman Catholic faith.

Ho-kay then.

But we're not done with Angela yet.

Her work can also be found at Breast Cancer Prevention Foundation, of which with Joel Brind (see above) she's a co-founder and at the Association for Interdisciplinary Research inValues and Social Change, which at least has the grace to admit that it is a 'pro-life' organization.
The Association for Interdisciplinary Research in Values and Social Change is a professional organization for pro-life researchers and educators which offers a forum to exchange ideas of scientific and social science disciplines. The Association is a network of pro-life professionals who encourage research and academic publication and the development of textbooks and curricula for high schools and colleges. Since its 1986 inception, the Association has published a quarterly news bulletin which has done extensive academic work, especially on Post-Abortion Syndrome (PAS), a pattern of psychological problems suffered by some women and men after abortion. Professional research and writing on PAS is vitally important because it is an emerging new field.

(PAS is complete bullshit, BTW, again debunked countless times.)

Vellacott likes Angela. He brought her to Parliament Hill in 2007 to lecture on the inevitable cancer/abortion link.

We've saved the best for last. Four of the eleven references are to our old pal and professional liar-for-hire Priscilla Coleman, who is Perfesser of Home Ec and Abortion Trauma for Sluts.

Priscilla is aaaall over the newly announced World Expert Consortium for Abortion Research and Education, or 'wecare' for short. (Awww.)

She is ubiquitous in the articles and publications sections and is the ONLY person in the presentations section.

She is obviously making hay with her recent notoriety occasioned by the publication of a piece of typical bullshit in the 'prestigious' British Journal of Psychiatry, which is celebrating its bicentennial with a bit of hubbub about that very paper.

The editor says:
We have seldom been a campaigning journal, because campaigning, even in pursuit of a noble cause, indicates partiality, and we also like to think that we are independent of the many lobbying groups that surround our subject, even though we sometimes venture into territory occupied by factional fighting, as illustrated for example in the correspondence in this issue (Howard et al, p. 74, etc.) over a paper we published in September.

Annoyingly, that from the editor is the only bit not behind the sub wall. I've put out a twitter call for someone with a sub (and repeat it here) to clue us on on what transpires in eight letters, an editors' response, and and an author's reply.

There have been many calls for BJP to retract the paper, as the Lancet had to over the fraudulent work of Andrew Wakefield on the vaccine-autism non-link.

Somehow I doubt BJP will have the balls of the The Lancet.

Anyway, to cut to the chase, bravo to CTV for 'ignoring' a bunch of science-for-hire bullshit. These people need to be exposed every time they weasel their way into serious, grown-up discussions.

Again, we say: THIS is precisely why we won't debate them. Because they lie.

UPDATE: Ain't the twittersphere grand? Thanks to goddammitkitty for PDFs of BJP letters, editor's reply, and author's response. New blogpost coming.

UPDATE UPDATED: British Journal of Psychiatry ^NOT 'Prestigious'.

*Correction: From Dr. Dawg, we learn that the Ostbye study is not completely irrelevant. There was a control group of women who did not have abortions. But the conclusion is the same. The complication rate for abortion is low.

From Dr. Dawg's link we also learn that they've been pumping the same old crap for ages.